Consequences of in vitro culture conditions on embryo development and quality.

@article{Rizos2008ConsequencesOI,
  title={Consequences of in vitro culture conditions on embryo development and quality.},
  author={Dimitrios Rizos and Monica Clemente and Pablo Bermejo-{\'A}lvarez and Julio De la Fuente and Patrick Lonergan and Alfonso Guti{\'e}rrez-Ad{\'a}n},
  journal={Reproduction in domestic animals = Zuchthygiene},
  year={2008},
  volume={43 Suppl 4},
  pages={44-50}
}
Despite major efforts directed at improving the yield of blastocysts from immature oocytes in vitro, the quality of such blastocysts continually lags behind that of blastocysts produced in vivo. These differences are manifested at the level of morphology, metabolism, gene expression and cryotolerance, and may have a knock-on effect further along the developmental axis. Evidence suggesting that in vitro culture conditions, while capable of producing blastocysts in relatively high numbers, are… CONTINUE READING

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