Consequences of brief ischemia: stunning, preconditioning, and their clinical implications: part 2.

@article{Kloner2001ConsequencesOB,
  title={Consequences of brief ischemia: stunning, preconditioning, and their clinical implications: part 2.},
  author={Robert A. Kloner and Robert B. Jennings},
  journal={Circulation},
  year={2001},
  volume={104 25},
  pages={3158-67}
}
In experimental studies in the dog, total proximal coronary artery occlusions of up to 15 minutes result in reversible injury, meaning that the myocytes survive this insult. The 15 minutes of ischemia, however, induce numerous changes in the myocardium, including certain monuments to the brief episode of ischemia that may persist for days. One of these monuments is stunned myocardium, which represents "prolonged postischemic contractile dysfunction of myocardium salvaged by reperfusion." The… CONTINUE READING

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