Consequences of axonal transport blockade by batrachotoxin on mammalian neuromuscular junction. III. An ultrastructural study

@article{Hudson1984ConsequencesOA,
  title={Consequences of axonal transport blockade by batrachotoxin on mammalian neuromuscular junction. III. An ultrastructural study},
  author={Catherine S Hudson and Sharad S. Deshpande and Edson X. Albuquerque},
  journal={Brain Research},
  year={1984},
  volume={296},
  pages={319-332}
}
Ultrastructural alterations were analyzed following a single subperineural injection of batrachotoxin (BTX) into the rat peroneal nerve 10-12 mm proximal to its entrance into the extensor digitorum longus (EDL) muscle. At the injection site, most axons underwent reversible changes. Internodal segments of myelin degenerated and were phagocytized without apparent damage to the axon cylinders. Newly forming myelin sheaths were observed by 10 days after injection. Similarly, motor endplates were… CONTINUE READING

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