Consequences of Keratin Phosphorylation for Cytoskeletal Organization and Epithelial Functions.

@article{Sawant2017ConsequencesOK,
  title={Consequences of Keratin Phosphorylation for Cytoskeletal Organization and Epithelial Functions.},
  author={Mugdha Sawant and Rudolf E. Leube},
  journal={International review of cell and molecular biology},
  year={2017},
  volume={330},
  pages={171-225}
}
Intermediate filaments are major phosphoproteins. The complex patterns of intermediate filament phosphorylation make up a poorly understood code reflecting cytoskeletal properties and cellular function through an intense crosstalk with multiple signaling pathways. This review focuses on the epithelial keratin intermediate filaments highlighting the tight-knit relationship of keratin phosphorylation and network organization during cell division and apoptosis, and the importance of keratin… CONTINUE READING