Consensus statement on the management of chronic hand eczema

  title={Consensus statement on the management of chronic hand eczema},
  author={John English and R Aldridge and D J Gawkrodger and Stephen Kownacki and Barry N. Statham and J White and J. D. L. Williams},
  journal={Clinical and Experimental Dermatology},
The management of chronic hand eczema is often inadequate. There are currently no evidence‐based guidelines specifically for the management of chronic hand eczema, and evidence for established treatments for hand eczema is not of sufficient quality to guide clinical practice. This consensus statement, based on a review of published data and clinical practice in both primary and secondary care, is intended to guide the management of chronic hand eczema. It describes the epidemiology and… 

Guidelines for diagnosis, prevention and treatment of hand eczema

  • T. DiepgenK. Andersen T. Agner
  • Medicine
    Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
  • 2015
Topical corticosteroids are recommended as first line treatment in the management of HE, however continuous long‐term treatment beyond six weeks only when necessary and under careful medical supervision is recommended.

Topical Treatment of Hand Eczema: Corticosteroids

There is a clear need for good-quality randomized controlled trials on existing and new treatment options for hand eczema, which can increase the risk of adverse effects.

Management of Chronic Hand Eczema.

Alitretinoin for the treatment of severe chronic eczema of the hands

Alitretinoin can be considered as a valid therapeutic option for the treatment of CHE in patients not responding to ordinary treatments, and acts effectively on both objective and subjective clinical signs, resulting in a significant improvement in QoL of patients.

Interventions for hand eczema.

Irradiation with ultraviolet (UV) light: local combination ultraviolet light therapy (PUVA) may lead to improvement in investigator-rated symptom control when compared to local narrow-band UVB after 12 weeks of treatment (RR 0.76, 95% CI 0.82 to 6.06), including application site burning/pruritus.

Management of chronic hand and foot eczema. An Australia/New Zealand Clinical narrative

Management of chronic hand/foot eczemas extends beyond mere pharmacological or physical treatment, and requires an encompassing approach including removal or avoidance of causative factors, behavioural changes and social support.

Treatment of severe, chronic hand eczema: results from a UK‐wide survey

The results indicated that the treatment approaches favoured by UK dermatologists differ, and Psoralen combined with ultraviolet A (PUVA) and alitretinoin were identified as the most frequent first‐line treatment options for hyperkeratotic HE, whereas oral corticosteroids were identified for vesicular HE.

Drugs for the Treatment of Chronic Hand Eczema: Successes and Key Challenges

Chronic hand eczema patients may benefit from new topical and systemic therapeutics that specifically target abnormally expressed immune markers that are under investigation in recently completed or currently ongoing trials.

[Management of chronic hand eczema].

  • M. Lahfa
  • Medicine
    Annales de dermatologie et de venereologie
  • 2014

Comparison of ALitretinoin with PUVA as the first-line treatment in patients with severe chronic HAnd eczema (ALPHA): study protocol for a randomised controlled trial

Introduction Hand eczema (HE) is one of the most common skin disorders and an important cause for morbidity and occupational disability. The 1-year prevalence of HE is estimated to be up to 10% and



Long‐term, intermittent treatment of chronic hand eczema with mometasone furoate

It is concluded that long‐term, intermittent treatment of chronic hand eczema with mometasone furoate fatty cream is effective and safe.

Comparison of cyclosporine and topical betamethasone-17,21-dipropionate in the treatment of severe chronic hand eczema.

Low-dose cyclosporine at 3 mg/kg/day is as effective as topical BDP in the treatment of chronic hand Eczema and could be useful as an alternative treatment for severe chronic hand eczema in patients unresponsive to conventional treatment.

Intermittent maintenance therapy in chronic hand eczema with clobetasol propionate and flupredniden acetate.

It is suggested that an intermittent schedule is advantageous when using a corticosteroid of high potency when keeping the dermatitis in remission.

Successful treatment of dyshidrotic hand eczema using tap water iontophoresis with pulsed direct current.

Only those sides treated with tap water iontophoresis showed significant improvement, indicating the efficacy of this treatment in cases of dyshidrotic hand eczema.

Chronic eczematous dermatitis of the hands: a comparison of PUVA and UVB treatment.

PUVA and UVB treatments are alternative treatment modalities in patients with recalcitrant chronic eczematous dermatitis of the hands and PUVA is superior to UVB.

Hand eczema and long-term prognosis in atopic dermatitis.

  • I. Rystedt
  • Medicine
    Acta dermato-venereologica. Supplementum
  • 1985
It is concluded that the serum IgE cannot be used to establish the diagnosis of atopic dermatitis, and there was a strong correlation between the extent of persistent dermatitis and serum Ig E levels.

Treatment of hyperkeratotic dermatitis of the palms (eczema keratoticum) with oral acitretin. A single-blind placebo-controlled study.

It is concluded that 30 mg of acitretin is efficacious and safe to use in patients with hyperkeratotic dermatitis of the palms, and after 4 weeks of treatment, a 51% reduction of all symptoms was observed among patients receiving ac itretin.

Topical tacrolimus (FK506) and mometasone furoate in treatment of dyshidrotic palmar eczema: a randomized, observer-blinded trial.

Treatment with FK506 offers the possibility for rotational therapy with mometasone furoate in long-standing cases of chronic dyshidrotic palmar eczema.

Epidemiology of hand eczema in an industrial city.

  • B. Meding
  • Medicine
    Acta dermato-venereologica. Supplementum
  • 1990
A multiple logistic regression analysis revealed that the most important predictive factor for hand eczema was female sex, followed by occupational exposure, a history of asthma and/or hayfever and a service occupation, which was shown to be a long-lasting disease with a relapsing course.

Overview of studies of treatments for hand eczema—the EDEN hand eczema survey

A large number of interventions ranging from topical steroids to oral ciclosporin are used, but their evidence base and the best methods to assess their efficacy are uncertain.