Consensus guidelines for the conduct and reporting of clinical trials in systemic light-chain amyloidosis

@article{Comenzo2012ConsensusGF,
  title={Consensus guidelines for the conduct and reporting of clinical trials in systemic light-chain amyloidosis},
  author={Raymond L. Comenzo and Donna E. Reece and Giovanni Palladini and Donald Seldin and Vaishali Sanchorawala and Heather Landau and Rodney Howard Falk and Kerry Wells and Alan Solomon and Ashutosh D Wechalekar and Jeffrey A Zonder and Angela Dispenzieri and M Gertz and Howard Z. Streicher and Marilyn D. Skinner and Robert A Kyle and Giampaolo Merlini},
  journal={Leukemia},
  year={2012},
  volume={26},
  pages={2317-2325}
}
This manuscript summarizes the recommendations that emerged from the first Roundtable on Clinical Research in Immunoglobulin Light-chain Amyloidosis (AL), a meeting sponsored by the Amyloidosis Foundation (Clarkston, MI, USA) to develop a consensus of experts on a modern framework for clinical trial design and drug development in AL. Recent diagnostic and technical advances in AL, and updated consensus guidelines for assessing hematologic and organ responses, enable us to define study… CONTINUE READING