Consanguinity and the Developmental Origins of Health and Disease

  title={Consanguinity and the Developmental Origins of Health and Disease},
  author={James S. Chisholm and Alan H. Bittles},
Background. Consanguineous marriage is strongly favored in many regions of the world, despite the prevalent Western belief that the progeny of close kin unions experience developmental disorders and premature mortality. Objective. We outline an alternative perspec- tive on the association between consanguinity and disease, in terms of life history theory and the developmental origins of health and disease. Methods. Meta-analyses of 64 studies across 14 countries and four continents were… 

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