Connexins in vascular physiology and pathology.

  title={Connexins in vascular physiology and pathology.},
  author={Anne C. Brisset and Brant E Isakson and Brenda R Kwak},
  journal={Antioxidants & redox signaling},
  volume={11 2},
Cellular interaction in blood vessels is maintained by multiple communication pathways, including gap junctions. They consist of intercellular channels ensuring direct interaction between endothelial and smooth muscle cells and the synchronization of their behavior along the vascular wall. Gap-junction channels arise from the docking of two hemichannels or connexons, formed by the assembly of six connexins, and achieve direct cellular communication by allowing the transport of small metabolites… CONTINUE READING
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