Connexins in lymphatic vessel physiology and disease.

  title={Connexins in lymphatic vessel physiology and disease.},
  author={Merlijn J Meens and Am{\'e}lie Sabine and Tatiana V Petrova and Brenda R Kwak},
  journal={FEBS letters},
  volume={588 8},
Connexins are transmembrane proteins that form gap junction- and hemi-channels. Once inserted into the membrane, hemi-channels (connexons) allow for diffusion of ions and small molecules (<1 kDa) between the extracellular space and the cytosol. Gap junction channels allow diffusion of similar molecules between the cytoplasms of adjacent cells. The expression and function of connexins in blood vessels has been intensely studied in the last few decades. In contrast, only a few studies paid… CONTINUE READING

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