Connexins form functional hemichannels in porcine ciliary epithelium.

  title={Connexins form functional hemichannels in porcine ciliary epithelium.},
  author={Mohammad Shahidullah and Nicholas A. Delamere},
  journal={Experimental eye research},
The expression of connexins in the ciliary epithelium is consistent with gap junctions between the pigmented (PE) and nonpigmented ciliary epithelium (NPE) that form when connexon hemichannels from adjacent cells pair to form a channel. Here we present evidence that suggests undocked connexons may form functional hemichannels that permit exchange of substances between NPE and the aqueous humor. Intact porcine eyes were perfused via the ciliary artery and propidium iodide (PI) (MW 668) was added… CONTINUE READING