Connexins and steroidogenesis in mouse Leydig cells.

  title={Connexins and steroidogenesis in mouse Leydig cells.},
  author={Dan Li and Poonampreet Sekhon and Kevin J. Barr and Lucrecia M{\'a}rquez-Rosado and Paul D Lampe and Gerald M. Kidder},
  journal={Canadian journal of physiology and pharmacology},
  volume={91 2},
Connexin43 has been recognized as forming gap junctions in Leydig cells. However, previous work has shown that mouse Leydig cells lacking this connexin do not suffer any limitation of their ability to produce testosterone when stimulated with luteinizing hormone. The objective of this study was to identify additional connexins in mouse Leydig cells that could be required for steroidogenesis. A reverse transcription - polymerase chain reaction screen involving isolated adult Leydig cells… CONTINUE READING