Connexin45 (alpha 6) expression delineates an extended conduction system in the embryonic and mature rodent heart.

@article{Coppen1999Connexin456,
  title={Connexin45 (alpha 6) expression delineates an extended conduction system in the embryonic and mature rodent heart.},
  author={Steven R. Coppen and Nicholas J. Severs and Robert G Gourdie},
  journal={Developmental genetics},
  year={1999},
  volume={24 1-2},
  pages={82-90}
}
We previously demonstrated that alpha 6 (Cx45), one of the three connexins of the mammalian myocardium, is preferentially expressed in the peripheral portion of the ventricular conduction system in rats and mice. Here we report that alpha 6 is also prominently immunolocalized in the atrioventricular node and His bundle of these species. The distribution of immunolocalized alpha 6 reveals that the node and bundle form part of an extended central conductive network circumscribing the AV and… CONTINUE READING

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