Connexin expression in cultured neonatal rat myocytes reflects the pattern of the intact ventricle.

@article{Kwak1999ConnexinEI,
  title={Connexin expression in cultured neonatal rat myocytes reflects the pattern of the intact ventricle.},
  author={Brenda R. Kwak and Marjan J.A. van Kempen and Magali Th{\'e}veniau-Ruissy and Daniel Gros and Habo J. Jongsma},
  journal={Cardiovascular research},
  year={1999},
  volume={44 2},
  pages={
          370-80
        }
}
OBJECTIVE Primary cultures of neonatal rat ventricular myocytes have become a widely used model to examine a variety of functional, physiological and biochemical cardiac properties. In the adult rat, connexin43 (Cx43) is the major gap junction protein present in the working myocardium. In situ hybridization studies on developing rats, however, showed that Cx40 mRNA displays a dynamic and heterogeneous pattern of expression in the ventricular myocardium around birth. The present studies were… Expand
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