Connexin 43 mRNA expression in two experimental models of epilepsy.

  title={Connexin 43 mRNA expression in two experimental models of epilepsy.},
  author={Kost V. Elisevich and Sandra A. Rempel and Brien Smith and N Allar},
  journal={Molecular and chemical neuropathology},
  volume={32 1-3},
The expression of mRNA for connexin 43, a gap junction protein putatively found in astrocytes, is studied in two experimental models of epilepsy: the electrically kindled rat and the tetanus-toxin-injected rat. Rats were kindled by electrical stimulation of the amygdala to Racine class 5 seizures and divided into cohorts of three to undergo 3, 6, or 10 such events, respectively. Another two cohorts of rats received injections of tetanus toxin at strengths of 3 and 9 MLD50, respectively, into… CONTINUE READING


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