Connexin 43 is involved in the generation of human-induced pluripotent stem cells.

@article{Ke2013Connexin4I,
  title={Connexin 43 is involved in the generation of human-induced pluripotent stem cells.},
  author={Qiong Ke and Li Li and Bing Cai and Chang Liu and Yan Yang and Yong Gao and Weijun Huang and Xiaofeng Yuan and Tao Wang and Qi Zhang and Andrew L. Harris and Liang Tao and Andy Peng Xiang},
  journal={Human molecular genetics},
  year={2013},
  volume={22 11},
  pages={2221-33}
}
Although somatic cells can be successfully programmed to create pluripotent stem cells by ectopically expressing defined transcriptional factors, reprogramming efficiency is low and the reprogramming mechanism remains unclear. Previous reports have shown that almost all human connexin (CX) isoforms are expressed by human embryonic stem (hES) cells and that gap junctional intercellular communication (GJIC) is important for ES cell survival and differentiation. However, the CX expression profiles… CONTINUE READING
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