Connexin 40 Promoter-Based Enrichment of Embryonic Stem Cell-Derived Cardiovascular Progenitor Cells

  title={Connexin 40 Promoter-Based Enrichment of Embryonic Stem Cell-Derived Cardiovascular Progenitor Cells},
  author={R. David and H. Theiss and W-M Franz},
  journal={Cells Tissues Organs},
  pages={62 - 69}
  • R. David, H. Theiss, W-M Franz
  • Published 2008
  • Biology, Medicine
  • Cells Tissues Organs
  • Background: Pluripotent embryonic stem (ES) cells that can differentiate into functional cardiomyocytes as well as vascular cells in cell culture may open the door to cardiovascular cell transplantation. However, the percentage of ES cells in embryoid bodies (EBs) which spontaneously undergo cardiovascular differentiation is low (<10%), making strategies for their specific labeling and purification indispensable. Methods: The human connexin 40 (Cx40) promoter was isolated and cloned in the… CONTINUE READING
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