Connexin 30 sets synaptic strength by controlling astroglial synapse invasion

@article{Pannasch2014Connexin3S,
  title={Connexin 30 sets synaptic strength by controlling astroglial synapse invasion},
  author={Ulrike Pannasch and Dominik Freche and Glenn Dall{\'e}rac and Gr{\'e}gory Gh{\'e}zali and Carole Escartin and Pascal Ezan and Martine Cohen-Salmon and Karim Benchenane and Ver{\'o}nica Abudara and Amandine Dufour and Joachim H. R. L{\"u}bke and Nicole D{\'e}glon and Graham Knott and David Holcman and Nathalie Rouach},
  journal={Nature Neuroscience},
  year={2014},
  volume={17},
  pages={549-558}
}
Astrocytes play active roles in brain physiology by dynamic interactions with neurons. Connexin 30, one of the two main astroglial gap-junction subunits, is thought to be involved in behavioral and basic cognitive processes. However, the underlying cellular and molecular mechanisms are unknown. We show here in mice that connexin 30 controls hippocampal excitatory synaptic transmission through modulation of astroglial glutamate transport, which directly alters synaptic glutamate levels… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 3 times over the past 90 days. VIEW TWEETS

From This Paper

Topics from this paper.
73 Citations
54 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 73 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 54 references

from synapse to behavior

  • U. Pannasch, Rouach, N. Emerging role for astroglial networks in informati processing
  • Trends Neurosci. 36, 405–417
  • 2013

Altered expression of glutamate signaling, growth factor, and glia genes in the locus coeruleus of patients with major depression

  • R Bernard
  • Mol. Psychiatry
  • 2011

Similar Papers

Loading similar papers…