Connective tissue growth factor is overexpressed in muscles of human muscular dystrophy.

Abstract

The detailed process of how dystrophic muscles are replaced by fibrotic tissues is unknown. In the present study, the immunolocalization and mRNA expression of connective tissue growth factor (CTGF) in muscles from normal and dystrophic human muscles were examined with the goal of elucidating the pathophysiological function of CTGF in muscular dystrophy… (More)

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@article{Sun2008ConnectiveTG, title={Connective tissue growth factor is overexpressed in muscles of human muscular dystrophy.}, author={Guilian Sun and Kazuhiro Haginoya and Yanling Wu and Y. Chiba and Tohru Nakanishi and Akira Onuma and Yuko Sato and Masaharu Takigawa and Kazuie Iinuma and Shigeru Tsuchiya}, journal={Journal of the neurological sciences}, year={2008}, volume={267 1-2}, pages={48-56} }