Connective tissue growth factor is directly related to liver fibrosis.

@article{Hayashi2002ConnectiveTG,
  title={Connective tissue growth factor is directly related to liver fibrosis.},
  author={Nobukazu Hayashi and T Kakimuma and Yoshinao Soma and Gary R. Grotendorst and Keiji Tamaki and Mikiko Harada and Atsuyuki Igarashi},
  journal={Hepato-gastroenterology},
  year={2002},
  volume={49 43},
  pages={
          133-5
        }
}
BACKGROUND/AIMS Connective tissue growth factor is a mitogenic, chemotactic, and cell matrix-inducing factor for fibroblasts, and is exclusively and directly induced by transforming growth factor-beta 1. In skin fibrosis, connective tissue growth factor is thought to be a downstream effector of transforming growth factor-beta 1 that is directly involved in the proliferation of connective tissue cells and the accumulation of matrix. Our aim is to confirm the involvement of connective tissue… CONTINUE READING

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