Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders.

@article{Igarashi1996ConnectiveTG,
  title={Connective tissue growth factor gene expression in tissue sections from localized scleroderma, keloid, and other fibrotic skin disorders.},
  author={Ai Igarashi and Kiyoko Nashiro and Kanako Kikuchi and Shinichi Sato and Hironobu Ihn and M Fujimoto and Gary R. Grotendorst and Kazuhiko Takehara},
  journal={The Journal of investigative dermatology},
  year={1996},
  volume={106 4},
  pages={729-33}
}
Connective tissue growth factor (CTGF) is a novel peptide that exhibits platelet-derived growth factor-like activities and is produced by skin fibroblasts after activation with transforming growth factor-beta. Coordinate expression of transforming growth factor-beta followed by CTGF during wound repair suggests a cascade process for control of tissue… CONTINUE READING