Connective tissue growth factor (CTGF/CCN2): diagnostic and prognostic value in acute heart failure

@article{Behnes2013ConnectiveTG,
  title={Connective tissue growth factor (CTGF/CCN2): diagnostic and prognostic value in acute heart failure},
  author={Michael Behnes and Martina Brueckmann and Siegfried Lang and Christel Weiss and Parviz Ahmad-Nejad and Michael Neumaier and Martin Borggrefe and Ursula Hoffmann},
  journal={Clinical Research in Cardiology},
  year={2013},
  volume={103},
  pages={107-116}
}
As a mediator of ECM homeostasis, connective tissue growth factor (CTGF) appears to be involved in adverse structural remodeling processes in the heart. However, the diagnostic and prognostic value of CTGF levels in acute heart failure (AHF) in addition to natriuretic peptide testing has not yet been evaluated. A total of 212 patients presenting with acute dyspnea and/or peripheral edema to the Emergency Department were evaluated. CTGF and NT-proBNP plasma levels were measured at the initial… CONTINUE READING
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