Connective tissue changes in the cervix during normal pregnancy and pregnancy complicated by cervical incompetence.

@article{Rechberger1988ConnectiveTC,
  title={Connective tissue changes in the cervix during normal pregnancy and pregnancy complicated by cervical incompetence.},
  author={Tomasz Rechberger and Niels Uldbjerg and H R Witek Oxlund},
  journal={Obstetrics and gynecology},
  year={1988},
  volume={71 4},
  pages={563-7}
}
When postpartum cervical biopsy specimens were compared with biopsy specimens from nonpregnant women, they revealed a 12-fold decrease in mechanical strength, a 50% reduction in the concentrations of collagen and sulfated glycosaminoglycans, a 35% reduction in hyaluronic acid, an increase in collagen extractability, and a fivefold increase in collagenolytic activity. Primiparas with relatively high concentrations of collagen and hyaluronic acid had relatively long cervical dilatation times… CONTINUE READING
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