Connecting macroscopic dynamics with microscopic properties in active microtubule network contraction

@article{Foster2017ConnectingMD,
  title={Connecting macroscopic dynamics with microscopic properties in active microtubule network contraction},
  author={Peter J Foster and Wen Yan and Sebastian Furthauer and Michael J. Shelley and Daniel J. Needleman},
  journal={arXiv: Subcellular Processes},
  year={2017}
}
The cellular cytoskeleton is an active material, driven out of equilibrium by molecular motor proteins. It is not understood how the collective behaviors of cytoskeletal networks emerge from the properties of the network's constituent motor proteins and filaments. Here we present experimental results on networks of stabilized microtubules in Xenopus oocyte extracts, which undergo spontaneous bulk contraction driven by the motor protein dynein, and investigate the effects of varying the initial… Expand

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