Connecting drug delivery reality to smart materials design.

@article{Grainger2013ConnectingDD,
  title={Connecting drug delivery reality to smart materials design.},
  author={David William Grainger},
  journal={International journal of pharmaceutics},
  year={2013},
  volume={454 1},
  pages={521-4}
}
Inflated claims to both design and mechanistic novelty in drug delivery and imaging systems, including most nanotechnologies, are not supported by the generally poor translation of these systems to clinical efficacy. The "form begets function" design paradigm is seductive but perhaps over-simplistic in translation to pharmaceutical efficacy. Most… CONTINUE READING