Conjugation of the 15-kDa interferon-induced ubiquitin homolog is distinct from that of ubiquitin.


The biological effect of type 1 interferons is proposed to arise in part from the conjugation of ubiquitin cross-reactive protein (UCRP), the ISG15 gene product, to intracellular target proteins in a process analogous to that of its sequence homolog ubiquitin, a highly conserved 8.6-kDa polypeptide whose ligation marks proteins for degradation via the 26 S… (More)


Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.