Conjugated linoleic acids lower the release of eicosanoids and nitric oxide from human aortic endothelial cells.

@article{Eder2003ConjugatedLA,
  title={Conjugated linoleic acids lower the release of eicosanoids and nitric oxide from human aortic endothelial cells.},
  author={Klaus Eder and Sabine Schleser and Karin Becker and Ramona Koerting},
  journal={The Journal of nutrition},
  year={2003},
  volume={133 12},
  pages={
          4083-9
        }
}
The objective of this study was to determine the effects of cis-9, trans-11 and trans-10, cis-12 CLA on the release of vasoactive eicosanoids and nitric oxide (NO) in human aortic endothelial cells. Experiments were conducted in which cells were incubated with these fatty acids, and the concentrations of various eicosanoids [6-keto prostaglandin (PG) F(1alpha) as a stable product of PGI(2), thromboxane (TX) B(2) as a stable product of TXA(2), and PGE(2)] and NO in the medium were determined… CONTINUE READING
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