Conjugated linoleic acid attenuates the production and gene expression of proinflammatory cytokines in weaned pigs challenged with lipopolysaccharide.

@article{Changhua2005ConjugatedLA,
  title={Conjugated linoleic acid attenuates the production and gene expression of proinflammatory cytokines in weaned pigs challenged with lipopolysaccharide.},
  author={Lai Changhua and Yin Jindong and Li Defa and Zhao Lidan and Qiao Shiyan and Xing Jianjun},
  journal={The Journal of nutrition},
  year={2005},
  volume={135 2},
  pages={239-44}
}
We investigated the anti-inflammatory role of conjugated linoleic acid (CLA) in inflammation-challenged weaned pigs and in in vitro cultured peripheral blood mononuclear cells (PBMCs). To test the hypothesis that inflammation responses can be attenuated by dietary CLA supplementation, we used an acute inflammation model in which pigs were injected with lipopolysaccharide (LPS). After 14 d of dietary supplementation with either 2% soybean oil or 2% CLA, half of the pigs in each diet group were… CONTINUE READING

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