Conidiation Color Mutants of Aspergillus fumigatus Are Highly Pathogenic to the Heterologous Insect Host Galleria mellonella

@article{Jackson2009ConidiationCM,
  title={Conidiation Color Mutants of Aspergillus fumigatus
                    Are Highly Pathogenic to the Heterologous Insect Host Galleria
                        mellonella},
  author={Jennifer C. Jackson and Laura A. Higgins and Xiaorong Lin},
  journal={PLoS ONE},
  year={2009},
  volume={4},
  pages={101 - 112}
}
The greater wax moth Galleria mellonella has been widely used as a heterologous host for a number of fungal pathogens including Candida albicans and Cryptococcus neoformans. A positive correlation in pathogenicity of these yeasts in this insect model and animal models has been observed. However, very few studies have evaluated the possibility of applying this heterologous insect model to investigate virulence traits of the filamentous fungal pathogen Aspergillus fumigatus, the leading cause of… CONTINUE READING

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