Congestive heart failure: extent of cardiac functional changes caused by aging and organ dysfunction.

@article{Chantler2006CongestiveHF,
  title={Congestive heart failure: extent of cardiac functional changes caused by aging and organ dysfunction.},
  author={Paul D Chantler and David F. Goldspink and Richard Edward Clements and Linda Schaffner Sharp and Dominik Schlosshan and L-B Tan},
  journal={Heart},
  year={2006},
  volume={92 5},
  pages={
          686-8
        }
}
The mechanical function of the heart is known to deteriorate with increasing age and disease. After rigorous screening of necropsied hearts to exclude cardiovascular disease, Olivetti et al 1 in New York showed that about one third of the cardiomyocytes are lost from the human male heart between the ages of 17–90 years. This natural attrition contrasts with the loss incurred through myocardial infarction and cardiomyopathy, the most common causes of heart failure (HF) in western societies. We… CONTINUE READING
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