Congenital platelet disorders: overview of their mechanisms, diagnostic evaluation and treatment.

@article{Hayward2006CongenitalPD,
  title={Congenital platelet disorders: overview of their mechanisms, diagnostic evaluation and treatment.},
  author={Catherine P M Hayward and A Koneti Rao and Marco Cattaneo},
  journal={Haemophilia : the official journal of the World Federation of Hemophilia},
  year={2006},
  volume={12 Suppl 3},
  pages={128-36}
}
The bleeding problems associated with common and rare inherited platelet disorders illustrate the importance of platelets to normal haemostasis. At sites of injury, platelets normally adhere, undergo activation, secretion and aggregate formation, and they provide the membrane surface for the assembly of coagulation to generate thrombin. The causes of inherited disorders that alter platelet haemostatic functions are quite diverse, ranging from defects in receptors critical to platelet adhesion… CONTINUE READING

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