Congenital hypopituitarism: clinical, molecular and neuroradiological correlates.


OBJECTIVE Recent studies have suggested that mutations in genes encoding several hypothalamo-pituitary (H-P) transcription factors result in hypopituitarism [isolated GH deficiency (IGHD) and combined pituitary hormone deficiency (CPHD)], which may in turn be related to the neuroanatomy revealed by magnetic resonance (MR) imaging. Although studies have… (More)
DOI: 10.1111/j.1365-2265.2009.03572.x