Congenital estrogen deficiency in men: a new syndrome with different phenotypes; clinical and therapeutic implications in men

@article{Rochira2002CongenitalED,
  title={Congenital estrogen deficiency in men: a new syndrome with different phenotypes; clinical and therapeutic implications in men},
  author={V. Rochira and A. Balestrieri and B. Madeo and A. Spaggiari and C. Carani},
  journal={Molecular and Cellular Endocrinology},
  year={2002},
  volume={193},
  pages={19-28}
}
The report focuses on the role of estrogens in human male, dealing with two human models of congenital estrogen deficiency: estrogen resistance and aromatase deficiency. Similarities and differences of clinical phenotypes of these models are described and progresses of estrogen treatment of aromatase-deficient men are reported. Finally, the putative use of estrogen in men and the use of aromatase inhibitors and antiestrogen for male disorders are discussed. 
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