Congenital diaphragmatic hernia.

@article{Keijzer2010CongenitalDH,
  title={Congenital diaphragmatic hernia.},
  author={Richard Keijzer and Prem Lata Puri},
  journal={Seminars in pediatric surgery},
  year={2010},
  volume={19 3},
  pages={
          180-5
        }
}
Congenital diaphragmatic hernia (CDH) is a congenital anomaly consisting of a posterolateral defect in the diaphragm also known as a Bochdalek hernia. It occurs in 1 in 2000 to 3000 newborns and is associated with a variable degree of pulmonary hypoplasia (PH) and persistent pulmonary hypertension (PPH). Despite remarkable advances in neonatal resuscitation and intensive care and the new postnatal treatment strategies, many newborns with CDH continue to have high rates of mortality and… 
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Congenital Diaphragmatic Hernia
TLDR
The chapter will deal with both open and minimally invasive method of the repair of herniated abdominal viscera, and the management of pulmonary hypertension is outside the scope of this chapter.
Congenital Diaphragmatic Hernia
Congenital diaphragmatic hernia (CDH) is a defect of development of the pericardioperitoneal canals. In general, it occurs at 6–7 weeks of gestation. It is responsible for herniation of the abdominal…
Congenital Diaphragmatic Hernia
  • J. Tovar
  • Medicine
    Orphanet Journal of Rare Diseases
  • 2012
Congenital Diaphragmatic Hernia (CDH) is defined by the presence of an orifice in the diaphragm, more often left and posterolateral that permits the herniation of abdominal contents into the thorax.…
Extracorporeal membrane oxygenation in infants with congenital diaphragmatic hernia.
Congenital diaphragmatic hernia (CDH) is a severe congenital anomaly which impairs normal pulmonary development leading to acute and chronic respiratory failure, pulmonary hypoplasia, pulmonary…
Basic and translational science advances in congenital diaphragmatic hernia.
TLDR
This review focusses on the genetic, epigenetic and protein background and the latest advances in basic and translational aspects of CDH research.
Congenital asymptomatic diaphragmatic hernias in adults: a case series
TLDR
Patients who present with late diaphragmatic hernias complain of a wide variety of symptoms, and diagnosis may be difficult, so additional investigation and research appear necessary to better explain the development and progression of this type of disease.
Left congenital diaphragmatic hernia and gastroschisis in a term male infant
TLDR
A term male infant born to a healthy 24-year-old mother with antenatally diagnosed liver-up, left congenital diaphragmatic hernia, and gastroschisis is currently well and thriving at 11 months of age.
Bilateral congenital diaphragmatic hernia: prognostic evaluation of a large international cohort.
Right Bochdalek Hernia Associated with Kartagener Syndrome: Developmental and Clinical Observations
We present a novel case of the association of right-sided Bochdalek hernia, a diaphragmatic life-threatening malformation, and Kartagener syndrome, which is characterized by congenital…
Bilious emesis as presenting symptom of congenital diaphragmatic hernia in an 8-month-old
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References

SHOWING 1-10 OF 78 REFERENCES
Genetics of congenital diaphragmatic hernia.
  • D. Scott
  • Medicine
    Seminars in pediatric surgery
  • 2007
TLDR
Critical findings in the areas of clinical and basic research that highlight the importance of genetics in the development of CDH are reviewed and practical information is provided that can aid physicians and surgeons as they evaluate and care for patients with isolated, nonisolated, and syndromic forms ofCDH.
Fetal lung and diaphragm development in congenital diaphragmatic hernia.
TLDR
The current molecular and genetic background of lung formation, as well as a reflection of this knowledge towards CDH, are discussed.
Genetic factors in congenital diaphragmatic hernia.
TLDR
Key findings are examined that are likely to form the basis for future research in this field ofCDH, including evidence of the roles of specific genes in the development of CDH.
Genetic aspects of human congenital diaphragmatic hernia
TLDR
This review will provide a brief summary of diaphragm development and model organism work most relevant to human CDH and will primarily describe important human phenotypes associated withCDH and also provide recommendations for diagnostic evaluation of a fetus or infant with CDH.
The etiology of congenital diaphragmatic hernia: still largely unknown?
Successful repair in utero of a fetal diaphragmatic hernia after removal of herniated viscera from the left thorax.
TLDR
Almost 75 percent of fetuses with congenital diaphragmatic hernia detected before birth die despite optimal postnatal care, and the neonatal outcome is related to the degree of pulmonary hypoplasia from in utero lung compression, which is determined by the timing and volume.
Intrathoracic silo for the potential antenatal repair of diaphragmatic herniae with liver in the chest.
TLDR
This work describes a new procedure intended to reduce the liver gradually so that the ductus venosus is never acutely kinked and more normal rib cage mechanics may be maintained.
Congenital diaphragmatic hernia and retinoids: searching for an etiology
TLDR
The epidemiology and pathophysiology of human CDH, the metabolism of retinoids and the implications ofretinoids in the development of the diaphragm and lung are described and the existing evidence of a disruption of the retinoid-signaling pathway in CDH is described.
Molecular genetics of congenital diaphragmatic defects
TLDR
A review of recent advances in human and mouse genetics that have led to the identification of genes involved in CDH discusses potential mechanisms underlying the seemingly random combination of diaphragmatic, pulmonary, cardiovascular, and gonadal defects in patients with CDH.
Congenital diaphragmatic hernia. Epidemiology and outcome.
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