Congenital cardiac lesions involving systolic flow abnormalities are associated with platelet dysfunction in children.

@article{Bailly2014CongenitalCL,
  title={Congenital cardiac lesions involving systolic flow abnormalities are associated with platelet dysfunction in children.},
  author={David K. Bailly and Lynn K. Boshkov and Muhammad Mujeeb Zubair and Vanessa J C Rogers and Gurion Lantz and Laurie R. Armsby and A. Roger Hohimer and Julie Martchenke and Paul Sochacki and Stephen E.M. Langley},
  journal={The Annals of thoracic surgery},
  year={2014},
  volume={98 4},
  pages={
          1419-24
        }
}
BACKGROUND Shear stress-induced platelet dysfunction (PD) is prevalent among adults with aortic stenosis. Our aim was to determine whether abnormal platelet function was associated with specific congenital cardiac lesions in children. METHODS The charts of 407 children who had undergone cardiopulmonary bypass and had preoperative platelet function analysis were evaluated. Patients were assigned to 1 of 11 different lesion categories. Platelet dysfunction (PD) was defined as prolonged closure… CONTINUE READING

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