Confounding in studies of adverse reactions to vaccines.

@article{Fine1992ConfoundingIS,
  title={Confounding in studies of adverse reactions to vaccines.},
  author={Paul E. M. Fine and Robert K T Chen},
  journal={American journal of epidemiology},
  year={1992},
  volume={136 2},
  pages={
          121-35
        }
}
Several social and medical attributes are associated with both avoidance or delay of vaccination and an increased risk of adverse events such as sudden infant death syndrome or childhood encephalopathy. Studies that fail to control adequately for such confounding factors are likely to underestimate the risks of adverse events attributable to vaccination. This paper reviews the literature on studies of severe adverse events after the administration of pertussis antigen-containing vaccines, with… CONTINUE READING
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