Conformations and biological properties of apomorphine and its phenanthro [10, 1-b, c] azepine homologue

Abstract

11, 12-Dihydroxy-7-methyl-4, 5, 6, 7, 7a, 8-hexahydrophenanthro[10, 1-b, c]-azepine (2), a homologue of apomorphine (1), has been found to be devoid of dopaminergic effects. The biological differences between apomorphine and this homologue are explained in terms of differences in conformation of the two molecules.

DOI: 10.1007/BF01945809

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Cite this paper

@article{Berney1975ConformationsAB, title={Conformations and biological properties of apomorphine and its phenanthro [10, 1-b, c] azepine homologue}, author={Daniel M. Berney and T. J. Petcher and J. Schmutz and Heinz P. Weber and TV White}, journal={Experientia}, year={1975}, volume={31}, pages={1327-1328} }