Conformational diversity of the Goodpasture antigen, the noncollagenous-1 domain of the alpha3 chain of collagen IV.

@article{Calvete2006ConformationalDO,
  title={Conformational diversity of the Goodpasture antigen, the noncollagenous-1 domain of the alpha3 chain of collagen IV.},
  author={Juan J Calvete and Fernando Revert and Mario Blanco and Javier Cervera and C{\'e}line T{\'a}rrega and L Puig Sanz and Francisco Revert-Ros and Froil{\'a}n Granero and Enr{\'i}que P{\'e}rez-Pay{\'a} and Billy G Hudson and Juan Saus},
  journal={Proteomics},
  year={2006},
  volume={6 Suppl 1},
  pages={S237-44}
}
The noncollagenous-1 domain of the alpha3 chain of collagen IV networks of basement membranes is the target of an antibody-mediated inflammatory response in Goodpasture autoimmune disease. This domain when excised from basement membranes by bacterial collagenase digestion exists in two molecular forms, M(H) and M(L), that differ in cleavage site and… CONTINUE READING