Conformational differences between the methoxy groups of QA and QB site ubisemiquinones in bacterial reaction centers: a key role for methoxy group orientation in modulating ubiquinone redox potential.

@article{Taguchi2013ConformationalDB,
  title={Conformational differences between the methoxy groups of QA and QB site ubisemiquinones in bacterial reaction centers: a key role for methoxy group orientation in modulating ubiquinone redox potential.},
  author={Alexander T Taguchi and Patrick J. O'malley and Colin A. Wraight and Sergei A Dikanov},
  journal={Biochemistry},
  year={2013},
  volume={52 27},
  pages={
          4648-55
        }
}
Ubiquinone is an almost universal, membrane-associated redox mediator. Its ability to accept either one or two electrons allows it to function in critical roles in biological electron transport. The redox properties of ubiquinone in vivo are determined by its environment in the binding sites of proteins and by the dihedral angle of each methoxy group relative to the ring plane. This is an attribute unique to ubiquinone among natural quinones and could account for its widespread function with… CONTINUE READING