Conformational changes of the chromatin subunit.

Hydrodynamic studies on monomer chromatin subunits (v1) as a function of ionic strength (0.7 mM to 100 mM KCl) indicate two salt-dependent conformational transitions. An abrupt transition occurs at about 7.5 mM ionic strength. Decreasing the ionic strength from 10 to 5 mM results in a decrease in s20,w of the v1 from 11.1 to 9.9 S. The diffusion coefficient… (More)