Conformation of beta2glycoprotein I and its effect on coagulation.


β(2)glycoprotein I (β(2)GPI) is the major antigen in the antiphospholipid syndrome. It has been shown that β(2)GPI can adapt to different conformations, a circular, a S-shaped and a J-shaped conformation. In literature anticoagulant properties of β(2)GPI have been indicated, though there is no consensus on how β(2)GPI exerts a certain action. This article… (More)
DOI: 10.1016/j.thromres.2012.08.269


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@article{Ninivaggi2012ConformationOB, title={Conformation of beta2glycoprotein I and its effect on coagulation.}, author={Marisa Ninivaggi and Hilde Kelchtermans and Theo Lindhout and Bas de Laat}, journal={Thrombosis research}, year={2012}, volume={130 Suppl 1}, pages={S33-6} }