Conformation, action, and mechanism of action of neuromuscular blocking muscle relaxants.

@article{Lee2003ConformationAA,
  title={Conformation, action, and mechanism of action of neuromuscular blocking muscle relaxants.},
  author={Chingmuh Lee},
  journal={Pharmacology & therapeutics},
  year={2003},
  volume={98 2},
  pages={143-69}
}
Since curare was introduced into clinical anaesthesia in 1942, efforts to create better neuromuscular blocking (NMB) muscle relaxants have continued. Today, muscle relaxation remains a mainstay of modern anaesthesia and intensive care. Through manipulation of the traditional structure-action relationships, many new and improved muscle relaxants have been created, and several have been brought to clinical use. However, structure-action relationship is inconsistent and has its limits. Using… CONTINUE READING