Confocal microscopic analysis of the spindle and chromosome configurations of human oocytes matured in vitro.

@article{Li2004ConfocalMA,
  title={Confocal microscopic analysis of the spindle and chromosome configurations of human oocytes matured in vitro.},
  author={Yuan Li and Huai Liang Feng and Yi-Juan Cao and Guangjuan Zheng and Yong Yang and Steve Mullen and John Kenneth Critser and Zi-Jiang Chen},
  journal={Fertility and sterility},
  year={2004},
  volume={85 4},
  pages={
          827-32
        }
}
OBJECTIVE To assess the potential effects of in vitro maturation (IVM) of human oocytes on the meiotic spindle and associated chromosome configuration. DESIGN Prospective study. SETTING Hospital-based IVF center. PATIENT(S) Patients with polycystic ovary syndrome (PCOS) undergoing unstimulated and stimulated cycles of oocyte retrieval. INTERVENTION(S) Immature (germinal vesicle and metaphase I) and mature (metaphase II) oocytes were collected from PCOS patients. The meiotic spindle and… CONTINUE READING
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