Confocal laser scanning analysis of an equine oral mast cell tumor with atypical expression of tyrosine kinase receptor C-KIT.

@article{Seeliger2007ConfocalLS,
  title={Confocal laser scanning analysis of an equine oral mast cell tumor with atypical expression of tyrosine kinase receptor C-KIT.},
  author={Frank Seeliger and Oded Hess and Marcus Pr{\"o}psting and Hassan Y Naim and Sven Kleinschmidt and T Woehrmann and P G Germann and Wolfgang Baumgaertner},
  journal={Veterinary pathology},
  year={2007},
  volume={44 2},
  pages={225-8}
}
A 20-year-old female horse showed a nodular, firm, focal ulcerated mast cell tumor at the right dorsobuccal face of the tongue. Histologically, the nonencapsulated tumor consisted of dense, infiltrating aggregates of well-differentiated, Cresyl violet-positive mast cells accompanied by numerous eosinophils. Furthermore, they exhibited a strong, diffuse, intracytoplasmatic immunohistochemical signal for tryptase and a faint membrane-associated and perinuclear signal for tyrosine kinase receptor… CONTINUE READING