Confocal imaging of Schwann-cell migration along muscle-vein combined grafts used to bridge nerve defects in the rat.

@article{Fornaro2001ConfocalIO,
  title={Confocal imaging of Schwann-cell migration along muscle-vein combined grafts used to bridge nerve defects in the rat.},
  author={Michele Fornaro and Pierluigi Tos and Stefano Geuna and Maria Giuseppina Giacobini-Robecchi and Bruno Battiston},
  journal={Microsurgery},
  year={2001},
  volume={21 4},
  pages={153-5}
}
Schwann cells guide axonal regrowth during peripheral nerve repair. In a case of a nerve lesion with substance loss, a graft conduit is necessary to enable axons to reach the distal nerve stump. If a non-nervous autograft is used, the question arises as to the presence and origin of Schwann cells along the grafted tube. We addressed this issue using a tubulization technique based on the use of an autologous vein filled with fresh skeletal muscle for the repair of sciatic nerve defects in the… CONTINUE READING