Confocal examination of nonmelanoma cancers in thick skin excisions to potentially guide mohs micrographic surgery without frozen histopathology.

@article{Rajadhyaksha2001ConfocalEO,
  title={Confocal examination of nonmelanoma cancers in thick skin excisions to potentially guide mohs micrographic surgery without frozen histopathology.},
  author={Milind Rajadhyaksha and Gregg Menaker and Thomas J Flotte and Peter J. Dwyer and Salvador Gonz{\'a}lez},
  journal={The Journal of investigative dermatology},
  year={2001},
  volume={117 5},
  pages={1137-43}
}
Precise removal of nonmelanoma cancers with minimum damage to the surrounding normal skin is guided by the histopathologic examination of each excision during Mohs micrographic surgery. The preparation of frozen histopathology sections typically requires 20-45 min per excision. Real-time confocal reflectance microscopy offers an imaging method potentially to avoid frozen histopathology and prepare noninvasive (optical) sections within 5 min. Skin excisions ( approximately 1 mm thick) from Mohs… CONTINUE READING
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