Confirmation of uterotrophic activity of 3-(4-methylbenzylidine)camphor in the immature rat.

  title={Confirmation of uterotrophic activity of 3-(4-methylbenzylidine)camphor in the immature rat.},
  author={Helen Tinwell and Paul A Lefevre and Graeme J Moffat and Angela Burns and Jenny Odum and Tracey Spurway and George Orphanides and John V. Ashby},
  journal={Environmental Health Perspectives},
  pages={533 - 536}
In this study we found that the ultraviolet sunscreen component 3-(4-methylbenzylidine)camphor (4MBC) is uterotrophic in immature rats when administered by either subcutaneous injection or oral gavage. These data confirm earlier reports of uterotrophic activity for this agent when administered to immature rats in the diet or by whole-body immersion; however, they are in contrast to negative unpublished immature rat uterotrophic assay results. Data also indicate that 4MBC binds to isolated rat… CONTINUE READING

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