Confirmation of the high frequency of the TMPRSS2/ERG fusion gene in prostate cancer

@article{Soller2006ConfirmationOT,
  title={Confirmation of the high frequency of the TMPRSS2/ERG fusion gene in prostate cancer},
  author={M. Soller and M. Isaksson and P. Elfving and W. Soller and R. Lundgren and I. Panagopoulos},
  journal={Genes},
  year={2006},
  volume={45}
}
In a recent study by Tomlins et al., (2005), it was shown that a large subset of prostate cancer harbors the fusion genes TMPRSS2/ERG and TMPRSS2/ ETV1, generated through cryptic interand intrachromosomal rearrangements. A gene fusion of the 50 untranslated region of TMPRSS2 to ERG or ETV1 was identified in 23 (79%) of 29 prostate cancer samples. As yet, however, there have not been any confirmatory reports. In the present study, total RNA was extracted from 18 prostate adenocarcinoma biopsies… Expand
Detection of TMPRSS2:ERG fusion gene in circulating prostate cancer cells.
Duplication of the fusion of TMPRSS 2 to ERG sequences identifies fatal human prostate cancer
Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer
TMPRSS2-ERG gene fusion in prostate cancer.
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References

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