Confirmation of the association of the C4B null allelle in autism.

  title={Confirmation of the association of the C4B null allelle in autism.},
  author={Dennis Odell and Alma Maciulis and Adele Cutler and Louise Warren and William M. McMahon and Hilary Coon and Gene Stubbs and Kathy Henley and Anthony R. Torres},
  journal={Human immunology},
  volume={66 2},
The objective of this study was to examine and attempt to confirm our previous findings of an increased frequency of the C4B null allele (C4BQ0) in subjects with autism. Newly identified subjects from Utah and Oregon were studied. Families evaluated included 85 who had a child with autism and 69 control families. Of the subjects with autism studied, 42.4% carried at least one C4BQ0, compared with 14.5% of the control subjects (p = 0.00013), with a relative risk of 4.33. Over half of the C4B… CONTINUE READING
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