Confirmation of gestational exposure to alprazolam by analysis of biological matrices in a newborn with neonatal sepsis

@article{GarcaAlgar2007ConfirmationOG,
  title={Confirmation of gestational exposure to alprazolam by analysis of biological matrices in a newborn with neonatal sepsis},
  author={{\'O}. Garc{\'i}a-Algar and M. López-Vilchez and Itziar Mart{\'i}n and A. Mǔr and M. Pellegrini and R. Pacifici and S. Rossi and S. Pichini},
  journal={Clinical Toxicology},
  year={2007},
  volume={45},
  pages={295 - 298}
}
Background. Different biological matrices are suitable for drug testing in newborns presenting with an acute withdrawal syndrome. Case report. The newborn of a mother reporting alprazolam use during pregnancy presented with respiratory distress and clinical features consistent with neonatal withdrawal syndrome or neonatal sepsis of vertical transmission. Alprazolam and its main metabolite (α-hydroxyalprazolam) were detected in cord serum, neonatal urine and also in neonatal hair, meconium and… Expand
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