Confirmation of antidepressant potential of the selective β3 adrenoceptor agonist amibegron in an animal model of depression

@article{Overstreet2008ConfirmationOA,
  title={Confirmation of antidepressant potential of the selective $\beta$3 adrenoceptor agonist amibegron in an animal model of depression},
  author={David H. Overstreet and Jeanne Stemmelin and Guy Griebel},
  journal={Pharmacology Biochemistry and Behavior},
  year={2008},
  volume={89},
  pages={623-626}
}

Involvement of serotonin receptor subtypes in the antidepressant-like effect of beta receptor agonist Amibegron (SR 58611A): An experimental study

Evaluation of The Effects of Desipramine , Venlafaxine And Bupropion on Depression and Anxiety in Mice By Forced Swimming Test and Elevated Plus Maze Test

Depression and anxiety in mice was investigated using a classic tricyclic antidepressant, desipramine; a serotonin-norepinephrine reuptake inhibitor, venlafaxine; and a second-generation antidepressant agent that blocks the central reuptakes of noradrenaline and dopamine, bupropion.

Effects of mirabegron on depression, anxiety, learning and memory in mice.

Investigating the effects of mirabegron on depression, anxiety, learning and memory by using forced swimming test, elevated plus maze test, passive avoidance and Morris water maze in mice found that it might be clinically useful for the treatment of OAB in elderly patients that should use drugs against depression and anxiety, without disrupt learning andMemory.

References

SHOWING 1-10 OF 32 REFERENCES

Antidepressant-like effects of CRF1 receptor antagonist SSR125543 in an animal model of depression.

Stimulation of the β3-Adrenoceptor as a Novel Treatment Strategy for Anxiety and Depressive Disorders

It is demonstrated for the first time that the stimulation of the β3 receptor by SR58611A resulted in robust anxiolytic-like effects, which paralleled those obtained with the prototypical benzodiazepine anxIOlytic diazepam or chlordiazepoxide.

Antidepressant effects of citalopram and CRF receptor antagonist CP-154,526 in a rat model of depression.

Administration of antidepressants, diazepam and psychomotor stimulants further confirms the utility of Flinders Sensitive Line rats as an animal model of depression

Findings confirm the utility of F SL rats as an animal model of depression because the FSL rats do not appear to exhibit behaviors analogous to anxiety or schizophrenia and because they respond “therapeutically” to antidepressants and not psychomotor stimulants.

Activation of β2- and β3-Adrenergic Receptors Increases Brain Tryptophan

It is concluded that activation of either β2- or β3-adrenergic receptors, but not β1- adrenergic receptor, increases mouse brain tryptophan content.